HHV8-associated lymphoproliferative disorder in the peripheral blood
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چکیده
منابع مشابه
HHV8/EBV Coinfection Lymphoproliferative Disorder: Rare Entity with a Favorable Outcome
HHV8/EBV-associated germinotropic lymphoproliferative disorder (GLD) is a challenging diagnosis given its rarity, the particular clinical presentation, and the lack of expression of markers usually used in establishing hematopoietic lineage. We report a new case of HHV8/EBV GLD in an immunocompetent 78-year-old woman. The diagnosis was made in an incidentally discovered lymphadenopathy. Histolo...
متن کاملMulticentric Castleman disease, Kaposi sarcoma, hemophagocytic syndrome, and a novel HHV8-lymphoproliferative disorder.
The case of a 45-year-old man with HIV disease with bulky lymphadenopathy, fevers, and weight loss is presented. Immune reconstitution inflammatory syndrome was initially believed to be the cause, but the patient was found to suffer from Kaposi sarcoma, multicentric Castleman disease, hemophagocytic syndrome, and a newly described lymphoproliferative disorder. The diagnostic reasoning related t...
متن کامل[Senile EBV-associated B-cell lymphoproliferative disorder].
Epstein-Barrvirus (EBV)は1964年 にアフリカのバー キットリンパ腫培養細胞から発見された.そ の後,上 咽頭 がんや 胃がんなどとの関わ りも明らかにされ,歴 史的に最 も活発 に研究 がな されて きた ヒ トがん ウイルスhuman Cancer virusで あると言える.そ の明 らかな発癌 との関連 にも関わらず,EBVは 高度に普遍的なウイルスで もある. EBVは 主に唾液 を関した母子感染によって伝播 されると 考えられる.わ が国の25歳 以上の成人人口においては,ほ ぼ100%に 近い感染率を示す とされる. EBVと 血 液 リ ンパ 系 疾 患 との 関 わ りは 深 い.表1に, 主 なEBV関 連 血 液 リ ンパ 系 疾 患 を示 す.知 られ る 限 り リ ンパ 系 疾 患 が 主 体 で あ り,顆 粒 球 系 な ど他 ...
متن کاملKSHV- and EBV-associated germinotropic lymphoproliferative disorder.
Kaposi sarcoma-associated herpesvirus (KSHV) is known to be associated with 3 distinct lymphoproliferative disorders: primary effusion lymphoma (PEL), multicentric Castleman disease (MCD), and MCD-associated plasmablastic lymphoma. We report 3 cases of a previously undescribed KSHV-associated lymphoproliferative disorder. The disease presented as localized lymphadenopathy and showed a favorable...
متن کاملKSHV/HHV8-associated lymphomas.
This review looks at the current state of knowledge on primary effusion lymphoma (PEL) and other Kaposi sarcoma herpesvirus (KSHV)/human herpesvirus 8 (HHV8)-associated lymphomas. In 1995, KSHV DNA sequences were identified within a distinct subgroup of acquired immunodeficiency syndrome-related non-Hodgkin lymphomas localized in body cavities and presenting as pleural, peritoneal and pericardi...
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ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-04-837823